The IGF Zone Protocol – Metabolic Hormone Optimization Program was developed by our company ARC Pharma LLC, a group of experienced geriatric and consulting pharmacists and healthcare professionals. We developed this program to specifically treat and prevent the common underlying cause of weight gain, obesity, diabetes, cardiovascular/heart disease, viral infections and cancer. Our research indicates that underlying cause is due to a chronic imbalance in the metabolic hormones Growth-Hormone and Cortisol. Our program is the result of substantial research into the common underlying cause of these diseases that dieting alone cannot and does not resolve and how to improve patient outcomes.

Our extensive research has pinpointed the common underlying cause of these conditions and diseases as resulting from chronic long-term Growth-Hormone deficiency in adults that is Sedentary Acquired™. Chronic Adult Sedentary Acquired Growth-Hormone deficiency is a new third type of Growth-Hormone deficiency that was recently discovered and identified by ARC Pharma in our research and is the result of
human ever-increasing stationary and sedentary high-tech lifestyles over the past one hundred years.

The treatment of this Metabolic Hormone deficiency requires in, addition to diet and exercise modification, supplementation with Growth-Hormone boosting and Cortisol suppressing supplements and medications or the administration of low dose Growth-Hormone replacement therapy along with regular IGF-1 – IGFBP3 and Cortisol blood level testing to titrate and slowly increase GH/IGF-1 levels to what we have determined is their optimal level – in the range of 150-250 ng/ml. Our treatment program should ideally be administered as an adjunct therapy in addition to regular medication treatment of the symptoms of these diseases to eventually allow for medication treatment to be slowly reduced and ultimately withdrawn.

Our ever-increasing sedentary lifestyles have slowly and insidiously reduced our body’s normal and natural production of Growth-Hormone. Our research shows that at least 50% or more of our body’s normal Growth-Hormone production actually results from exercise and physical activity and not exclusively from simple loop feedback systems as once thought. The Growth-Hormone production from exercise and physical activity is linear and helps control our body’s energy storage needs among other benefits.

Growth-Hormone is our main metabolic hormone and in many respects in our body’s master hormone. It works in conjunction with and controls the production and effects of our stress/metabolic hormone Cortisol. As a result of our ever-increasing stationary and sedentary lifestyles especially over the last 100 years our bodies have produced less and less Growth-Hormone causing an imbalance in our energy storage system that has allow the stress/metabolic hormone Cortisol to elevate out of control. The result is weight gain, obesity, diabetes, cardiovascular/heart disease and susceptibility to viral infections and cancer due to impaired immune system function – specifically T Cell dysfunction.

Sedentary Acquired Growth-Hormone deficiency cannot be reversed by food deprivation dieting alone. That is why all weight loss programs that rely on food deprivation dieting to reverse weight gain and obesity fail. Sedentary Acquired Growth-Hormone deficiency can only be reversed with a comprehensive treatment program like the IGF Zone Protocol that targets and maintains healthy Growth-Hormone levels.

Through our research we have discovered that since Growth-Hormone and IGF-1 (Insulin-like Growth Factors – the most stable measurement of Growth-Hormone stimulation of liver function) were only actually discovered within the past 70 years and that researchers only tested for and surveyed levels of Growth-Hormone and IGF-1 levels in the population over the past 40 years or less, today’s recognized “healthy” levels of Growth-Hormone and IGF-1 are inaccurate and low because of our ever increasing stationary and sedentary lifestyles. Neither is pituitary output testing of any value to determine normal levels of Growth-Hormone production outside of simply verifying that the pituitary is functioning at all to produce Growth-Hormone.

In reality, normal and healthy Growth-Hormone and IGF-1 levels can only be determined when levels found in the population are graphed in conjunction with the patient’s corresponding homeostasis model assessment of insulin resistance score (HOMA-IR). When graphed in such a fashion in studies of 1000’s of individuals, it becomes clear that insulin resistance – the leading cause of weight gain and type two diabetes – is least in those individuals who have an IGF-1 score of between 150-250ng/ml. It has been found that individuals with IGF-1 scores below 150ng/ml and above 250ng/ml are increasingly susceptible to insulin resistance, weight gain and type two diabetes and therefore it is critical to help patients to maintain an IGF-1 score in the range of 150-250ng/ml.

So how exactly does chronic Growth-Hormone deficiency lead to these conditions and diseases? Again, Growth-Hormone is in reality the body’s master hormone. One of Growth-Hormone’s main roles is to control Cortisol production and Cortisol’s effects on the body. Cortisol is a stress/metabolic hormone and is an atherosclerotic agent meaning that it is directly responsible for plaque buildup in our arteries. Chronically high Cortisol levels leads to low circulating levels of HDL that helps the body maintain normal Cholesterol levels and functioning and helps transport excess Cholesterol back to the liver. As a result patients with high Cortisol levels and low HDL levels suffer from plaque buildup in their arteries and are susceptible to high blood pressure, strokes and heart attacks.

Another major function of Growth-Hormone is that together with Cortisol, Growth-Hormone helps maintain our body’s energy storage system. Thus both Growth-Hormone and Cortisol are our two main metabolic hormones. Cortisol is primarily responsible for the conversion and storage of excess sugar for energy into visceral fat while Growth-Hormone acts to reverse that process by making visceral fat (stored sugar energy) available during strenuous exercise and physical activity. When exercise and physical activity become diminished long term so does Growth-Hormone production that regulates Cortisol’s conversion of sugar into visceral fat leading to insulin resistance, weight gain, obesity and type two diabetes. It is estimated that in excess of 50% of the population of the United States suffers from obesity and our research findings indicate that in excess of 50% of the population of the United States suffers from Sedentary Acquired Growth-Hormone deficiency!

Finally, we are in the midst of surging pandemic of viral infections and out of control cancer rates! Both are directly caused by our body’s inability to contain and destroy the viral invaders that cause these diseases. Our immune systems T Cells are responsible for destroying invading viral/cancer cells and are being hampered in this function by obesity and diabetes both caused by Growth-Hormone deficiency. Growth-Hormone deficiency has been proven to be the primary cause of the dysfunction and shutdown of the Thymus gland that is responsible for healthy T Cell immune system function. Likewise supplementation and adjunct administration of low dose Growth-Hormone
replacement therapy has been proven to substantially increase healthy T Cell immune system function to better fight these diseases.

Physicians today are in a conundrum! They simply treat the patient’s symptoms and maintain the disease state! Therefore it’s up to patients to take control of their health! Take control of your health with the IGF Zone Protocol – Metabolic Hormone Optimization Program developed by ARC Pharma LLC to help boost immune system function, prevent disease and promote weight loss! Contact us today – your body will thank you!